The British actor, 31, stars in the upcoming reboot as Prince Adam who, after being sent to live on earth as a baby, uncovers his destiny as superhero and alter ego He-Man, the protector of his home planet Eternia.
Centring around the origin story of He-Man, it follows the superhero as he prepares for battle to defend his planet from the forces of evil, which include villain Skeletor, played by Suicide Squad's Jared Leto.
The upcoming film is a reboot of the 1987 original which starred Swedish actor Dolph Lundgren and was based on the franchise from entertainment company Mattel, which created a number of animated series and comics.
Speaking on the red carpet at the UK premiere in central London, Galitzine praised director Travis Knight for adapting more than 130 episodes from the original series into the upcoming film.
"He assembled a team of people who were really very focused on creating fan service for the existing fans, but also making a movie that felt modern, that felt current," Galitzine told the Press Association.
"When it came to He-Man, we wanted to make a guy who obviously was still musclebound but had a sensitivity to him, had an accessibility to him that maybe we didn't quite feel in the past."
He added that landing the blockbuster role was an "incredible honour" and he was determined to "create a character who felt accessible, who felt current, who we could relate to in a lot of ways".
"I really feel like we've done that with this movie. So I'm just incredibly proud, and I hope people love watching it as much as I loved making it," he said.
The film also stars Luther actor Idris Elba as He-Man's ally, Duncan or Man-At-Arms, along with Riverdale actor Camila Mendes as Adam's protector, Teela.
"I love her origin story, I feel like that was very inspiring," Mendes said of Teela's original legacy appearance.
"I think something that I feel like we really stay true to is that Teela is very stubborn and hot-headed and she's a leader in the filmation cartoon and I feel like that definitely translates in the film as well.
"Also, this idea that she sees the goofiness of Prince Adam and really admires that and also wants a man like He-Man who is strong and courageous.
"Something she says throughout the series is 'Oh I wish there was a guy who was both of those things' because she doesn't know that he is both of those things.
"I feel like those sensibilities I really absorbed."
Other cast members include Together actor Alison Brie, who portrays supervillain Evil-Lyn, Bridesmaids star Kristen Wiig who voices Roboto, and Deadpool's Morena Baccarin.
