Giants spearhead Hogan won't be causing trouble for Hawthorn on Friday night, sidelined from the club's first trip to the MCG this season after fracturing his finger.
Kingsley can at least find some reprieve with Max Gruzewski to slot back into the side after the youngster had suffered his own hand fracture.
Hogan's finger fracture is just the latest setback for the 31-year-old, who had missed a month of football due to a hip injury.
Last round's 23-point loss to Carlton was just Hogan's second game back, with the 2024 Coleman Medallist first splitting the webbing in his right hand before fracturing his finger in a separate incident.
Hogan, who also missed the club's round-six Sydney derby with a quad issue, has undergone surgery and is sidelined for an indefinite period.
He had struggled to recapture his best form in his two games against St Kilda and Carlton, kicking one goal in each for a total of 12 majors from nine matches.
Key defender Jayden Laverde is also sidelined for at least three weeks with a hamstring strain.
"He's (Hogan) clearly frustrated. It hasn't been the ideal season for him," Kingsley said on Thursday.
"It wasn't the ideal pre-season with his preparation. It's one of those things where we've been fighting against it a little bit.
"You feel like you get past something and then something else bobs up.
"It's been a very difficult year for him and for us, trying to manage that.
"He won't play for a few weeks at least. It could be longer than that."
Gruzewski returns to the side after being dropped against St Kilda in favour of Hogan.
The 21-year-old had impressed in Hogan's absence from round nine, and kicked three goals twice in wins against Brisbane and Melbourne.
He makes a timely return from a hand injury to again replace Hogan.
"Max will be ready to go," Kingsley said.
"We're not blessed with keys at the moment. A few of them are injured.
"It's handy to have him available."
After a lacklustre outing against Carlton, the Giants face a litmus test against third-place Hawthorn (9-4) with a rare Friday night match at the MCG.
GWS had dominated the Hawks in their elimination final rematch, winning the opening-round fixture by 27 points.
But the sides have had opposite fortunes since, with the Giants languishing in 13th (6-8).
"You can live in hope, or you can do," Kingsley said.
"We're more about action, fixing the things that need to be fixed.
"In terms of history, it would suggest that Hawthorn games, particularly, are always close, within a goal or two, either way.
"We're expecting that again tomorrow night. We have been strong in the back half of seasons.
"Again, we're hoping that remains the same, but it doesn't come without hard work and preparation."
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