Penny Wong will fly out on Monday ahead of a week-long trip to Japan, China and South Korea, where trade and fuel security will be high on the agenda.
Senator Wong will meet with China's Foreign Minister Wang Yi in Beijing as part of annual talks.
"The Australian government remains committed to a stable and constructive relationship with China, which is in the interests of both our countries," she said.
"Australia and China have a comprehensive strategic partnership and benefit from deep economic ties, with our trade relationship underpinning supply chains, investment and livelihoods in both economies."
The talks come after China recently granted additional export licences to Australian beef producers, despite imposing a quota in January.
All imports of Australian beef into China after the quota is met will be hit with a 55 per cent tariff.
The foreign minister will also discuss energy markets with Japanese Foreign Minister Motegi Toshimitsu during meetings in Tokyo ahead of her Chinese visit.
"Australia and Japan are special strategic partners and close friends, with a relationship built on trust, aligned values, and mutual interests," Senator Wong said.
"Together, we support a free and open Indo-Pacific that is inclusive and resilient."
The Asian tour will finish with a trip to Seoul, where the foreign minister will meet with her South Korean counterpart Cho Hyu.
South Korea is one of Australia's prime sources of refined fuels, including petrol, diesel and aviation fuel.
The trip follows Prime Minister Anthony Albanese's recent visits to Southeast Asian nations to shore up fuel supplies during an oil crisis driven by the Iran War.
Japan, China and South Korea are top destinations for Australian gas exports and Canberra has been keen to reinforce the nation's status as a dependable supplier as it negotiates for greater fuel certainty.
"Australia will continue working with international partners to help secure the supplies we need – including diesel, petrol and fertiliser – and ensure Australia is prioritised as a reliable energy partner," Senator Wong said.
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